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Apart from fewer defibrillations for every patient to restore sinus rhythm following launch in the aortic cross-clamp during the amiodarone team, there were no considerable variations in surgical knowledge between the amiodarone and placebo groups (Table 2).

The amiodarone infusion started after the completion on the surgical course of action and significantly reduced the incidence of atrial fibrillation. Nonetheless, electrocardiographic monitoring was performed only during the 1st forty eight several hours just after surgical procedure, and amiodarone was discontinued in 18 % of clients on account of Negative effects.

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A Main limitation to your popular usage of oral amiodarone prophylaxis, nonetheless, could be the requirement of a 7-working day preoperative treatment period of time. Irrespective of whether an accelerated loading program of amiodarone about a duration of just one to two days just before surgery could possibly be successful and Secure in protecting against postoperative atrial fibrillation remains to generally be identified.

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